Dr Iain Oswald
Reader
Strathclyde Institute of Pharmacy and Biomedical Sciences
Personal statement
Iain D.H. Oswald graduated from the University of Edinburgh (2001) and remained there in the group of Professor Simon Parsons to study hydrogen-bonding patterns and co-crystallisation as part of his PhD. Fortunately, this research expanded to investigate the effects of high pressure which allowed him the opportunity to work at the European Synchrotron Radiation Facility in Grenoble. In 2004 he left for Grenoble where he became a postdoctoral researcher on the high pressure beamline (ID27). In 2006, he returned to Edinburgh to join the group of Colin R. Pulham and started a fellowship position funded by the Leverhulme Trust.
In 2009, Iain started his post at SIPBS as a Lecturer in Pharmaceutics and is interested and has been awarded funding in the areas of co-crystallisation of pharmaceutical materials at high pressure (EPSRC Early Career Fellowship, 2016-2021) and polymorphism and polymerisation of monomeric materials (Leverhulme Trust 2012-2015).
Iain has contributed to the MPharm program as the 4th Year Co-ordinator (2012-2016) and has been an integral part of the redevelopment of the MPharm curriculum. He was class coordinator for the 2nd year class Pharmaceutics (2013-2016) and for the Year 2 class Normal Function of the gastrointestinal tract (2012-2016). Students in the 4th year of study will be able to work with Iain on research associated with pharmaceutical products in the solid state. His teaching activities extend to postgraduate degrees in the MRes Drug Delivery Systems and MSc Pharmaceutical Analysis course.
He was a member of the ESPRC Early Career Forum in Manufacturing from 2016-2020. The Forum is an excellent way to engage with others at a similar stage. It seeks to engage with the EPSRC, Industry and academia to highlight challenges in the area of Manufacturing.
Prize And Awards
- EPSRC Early Career Fellowshop in Manufacturing the Future
- Recipient
- 1/6/2016
Publications
- Spatial and temporal visualization of polymorphic transformations in pharmaceutical tablets
- Gasol-Cardona Julia, Ward Martin R, Gutowski Olof, Drnec Jakub, Jandl Christian, Stam Danny, Maloney Andrew G P, Markl Daniel, Price Stephen W T, Oswald Iain D H
- Angewandte Chemie International Edition Vol 64 (2025)
- https://doi.org/10.1002/anie.202412976
- Calibration free approaches for rapid polymorph discrimination via low frequency (THz) Raman spectroscopy
- Chong Magdalene W S, Ward Martin R, McFarlan Catriona, Parrott Andrew J, Dallin Paul, Andrews John, Oswald Iain D H, Nordon Alison
- Chemical Communications Vol 61, pp. 925-928 (2024)
- https://doi.org/10.1039/D4CC05591H
- Exploring the effects of high pressure on hydrogen bonding in pharmaceutical cocrystals : a systematic study of pyridine dicarboxylic acid systems using synchrotron and neutron diffraction
- Ward Martin R, Bull Craig L, Funnell Nicolas P, Warren Mark R, Oswald Iain DH
- International Journal of Pharmaceutics Vol 647 (2023)
- https://doi.org/10.1016/j.ijpharm.2023.123514
- Freeze-induced phase transition and local pressure in a phospholipid/water system : novel insights from a time/temperature resolved synchrotron X-ray diffraction study
- Rodrigues Miguel A, Matsarskaia Olga, Rego Pedro, Geraldes Vitor, Connor Lauren E, Oswald Iain D H, Sztucki Michael, Shalaev Evgenyi
- Molecular Pharmaceutics Vol 20, pp. 5790-5799 (2023)
- https://doi.org/10.1021/acs.molpharmaceut.3c00657
- Pushing technique boundaries to probe conformational polymorphism
- Ward Martin R, Taylor Christopher R, Mulvee Matthew T, Lampronti Giulio I, Belenguer Ana M, Steed Jonathan W, Day Graeme M, Oswald Iain D H
- Crystal Growth and Design Vol 23, pp. 7217-7230 (2023)
- https://doi.org/10.1021/acs.cgd.3c00641
- Dual-cell, high-pressure studies of porous, flexible frameworks from 20 to 30,000 bar
- Ashworth David, Carrington Elliot J, McMonagle , Roseveare Thomas, Warren Mark, Fletcher Ashleigh, Moggach Stephen, Oswald Iain, Brammer Lee
- IUCr 2023 - 26th Congress and General Assembly of the International Union of Crystallography (2023)
Professional Activities
- Application of calibration free approaches for rapid polymorph discrimination by Raman spectroscopy
- Contributor
- 21/10/2024
- Application of calibration free approaches for rapid polymorph discrimination by low frequency Raman spectroscopy
- Contributor
- 25/4/2024
- Pharmaceuticals under high pressure
- Recipient
- 10/9/2021
- The Pharmacology of Harry Potter Potions
- Speaker
- 16/8/2021
- British Crystallographic Association Meeting (Event)
- Chair
- 1/4/2021
- European Science Foundation (Journal)
- Peer reviewer
- 1/7/2020
Projects
- Industrial CASE Account - University of Strathclyde 2022 | Fetah, Banaz
- Oswald, Iain (Principal Investigator) Markl, Daniel (Co-investigator) Fetah, Banaz (Research Co-investigator)
- 01-Jan-2022 - 01-Jan-2026
- KTP - GlaxoSmithKline plc. Understanding the different polymorphs in APIs which impact stability and biopharmaceutics.
- Markl, Daniel (Principal Investigator) Oswald, Iain (Co-investigator)
- 01-Jan-2022 - 31-Jan-2024
- Doctoral Training Partnership 2020-2021 University of Strathclyde | Tanveer, Saadia
- Florence, Alastair (Principal Investigator) Oswald, Iain (Co-investigator) Tanveer, Saadia (Research Co-investigator)
- 01-Jan-2022 - 01-Jan-2025
- Doctoral Training Partnership 2020-2021 University of Strathclyde | Chambers, Greg
- Perrie, Yvonne (Principal Investigator) Oswald, Iain (Co-investigator) Chambers, Greg (Research Co-investigator)
- 01-Jan-2020 - 01-Jan-2025
- Investigation of pyrazine:diacid co-crystal systems at high pressure
- Oswald, Iain (Principal Investigator) Ward, Martin (Co-investigator) Bull, Craig L. (Co-investigator) Funnell, Nicholas P. (Co-investigator)
- The aim of this proposal is to follow the changes in the hydrogen bonding
interaction in the pyrazine:oxalic acid and the Pyrazine:maleic acid co-crystals to complete our combined synchrotron and neutron study of the pyrazine:diacid
system. - 01-Jan-2020 - 06-Jan-2020
- Quantifying the Dynamic Response in Metal-Organic Frameworks (MOFs): A Platform for Tuning Chemical Space in Porous Materials
- Fletcher, Ashleigh (Principal Investigator) Oswald, Iain (Co-investigator)
- Quantifying the Dynamic Response in Metal-Organic Frameworks (MOFs): A Platform for Tuning Chemical Space in Porous Materials
- 01-Jan-2020 - 31-Jan-2024
Contact
Dr
Iain
Oswald
Reader
Strathclyde Institute of Pharmacy and Biomedical Sciences
Email: iain.oswald@strath.ac.uk
Tel: 548 2157